New publication in ACS Medicinal Chemistry Letters

New publication in ACS Medicinal Chemistry Letters

Check out the new Welab’s publication in the Virtual Special Issue from ACS Medicinal Chemistry Letters “Medicinal Chemistry in Portugal and Spain: A Strong Iberian Alliance”.

Piperazinyl Bicyclic Derivatives as Selective Ligands of the α2δ-1 Subunit of Voltage-Gated Calcium Channels. Ariadna Fernández, José Luis Díaz, Mónica García, Sergi Rodríguez-Escrich, Adriana Lorente, Raquel Enrech, Albert Dordal, Enrique Portillo-Salido, Mónica Porras, Begoña Fernández, Raquel F. Reinoso, José Miguel Vela, and Carmen Almansa. In this paper, the synthesis and pharmacological activities of a new series of compounds acting toward the α2δ-1 subunit of voltage-gated calcium channels (Cavα2δ-1) are reported, some of them showing improved analgesic efficacy-safety ratio in mice over pregabalin.

Link to the publication:

Dear colleagues, collaborators, and friends,

After more than 30 years of shared endeavours, in which we have grown personally and professionally, and with our emotions on the surface, we announce the closure of our company. We have travelled together through ups and downs, celebrated successes and overcome challenges as a team.

We extend our deepest gratitude to each of you for your dedication, passion, and commitment to a shared goal: discovering new treatments for the benefit and well-being of patients.

As we bid farewell, let’s cherish the memories we’ve created, the bonds we’ve formed, and the impact we’ve made together. Though our paths may diverge, the spirit of collaboration and camaraderie that defines our community will always endure.

We leave proud of the work accomplished and thank you for being an integral part of our journey, wishing you success in all your future challenges.

With heartfelt appreciation,

Welab’s team

We are proud to announce that Welab is partner of this new EU funded project.

In collaboration with 12 partners from 6 countries, Welab Barcelona is establishing the Antivirus Pandemic Preparedness EuropeAn pLatform (APPEAL), a European research initiative aimed at enhancing preparedness for future pandemics. This EU funded collaboration will establish a comprehensive program for the development of broad-spectrum antiviral drugs within a five year time frame ensuring drug affordability and accessibility to low income countries.
Link to the press release: