Scientists from the Pathology and Experimental Therapeutics Dept., Facultat de Medicina i Ciències de la Salut of the Universitat de Barcelona, and scientists from WeLab Barcelona have recently published the paper: “Development of a Novel σ1 Receptor Biosensor Based on Its Heterodimerization with Binding Immunoglobulin Protein in Living Cells” in a ACS Chemical Neuroscience special issue. The paper describes the development of a new Sigma-1 receptor-BiP biosensor as a simple and effective tool for exploring Sigma-1 receptor pharmacology in an easy cellular setting, which it has been something hard to achieve in the sigma field for many years. The biosensor is suitable for high-throughput applications and it may become a relevant tool in the sigma receptor field. Congratulations to Xavier Morato Arus, PhD, Victor Fernández Dueñas, Pilar Pérez Villamor, Marta Valle León, Jose Miguel Vela, Manuel Merlos, Javier Burgueño Hurtado and Francisco Ciruela.

Link to the publication: https://lnkd.in/ezXf_asE

#simga-1; #receptor; #oligomerization; #HTS; #pharmacology #pharmaceutical