R&D Platform

WeLab is Transforming Possibilities for Tomorrow


      Multiple Own Programs Aimed at Providing New Options for Millions of Patients

Tangible near-term value creation




Huntington's Disease

Multiple Sclerosis

Expansion to other diseases


Neuropathic Pain



Amyotrophic Lateral Sclerosis

Diabetic Retinopathy


Rett Syndrome

Additions and Eating disorders

Long-term discovery effors

Disease-modifying therapies supported on human genetics and novel targets addressing:

Neuronal loss


Pharmacological targets

We are expert on Sigma receptors field. There are two sigma receptors, sigma-1 and sigma-2, both are expressed in the CNS, regulate key aspects of neuronal survival in response to stress and are associated with various neurological disorders, including Alzheimer’s disease. Targeting sigma receptors has also emerged as a disease-modifying therapeutic strategy to prevent neurodegeneration. Moreover, the role of sigma-1 receptor in neuropathic pain has been widely demonstrated.

Besides sigma receptors, we are actively working on other targets and permanently exploring new opportunities relevant for our areas of interest.

WeLab Pipeline Multiple Value Inflections Mid-Term
PROJECT Compounds Hit Finding Hit to Lead Lead Optimization Candidate Profiling Pre-Clinic Development Clinical Phase I Clinical Phase II Clinical Phase III
Project WLB-52862 |||||||||||||||||| |||||||||||||||||| |||||||||||||||||| |||||||||||||||||| |||||||||||||||||| |||||||| Antiviral
Sigma2 WLB-89462 WLB-89362 |||||||||||||||||| |||||||||||||||||| |||||||||||||||||| |||||||||| Neurodegeneration
Sigma1 Agonist WLB-89134 WLB-87848 |||||||||||||||||| |||||||||||||||||| |||||||||||||||||| |||||||||| Neurodegeneration
Sigma2 + Sigma1ag WLB-89204 WLB89237 |||||||||||||||||| |||||||||||||||||| |||||||||||||||||| |||||||||| Neurodegeneration
Sigma2 + A2delta1 Neurodegeneration
Sigma1an + Sigma2 WLB-89286 |||||||||||||||||| |||||||||||||||||| |||||||||| Neuropsychiatry
Sigma1ag + NET WLB-77663 WLB-77769 |||||||||||||||||| |||||||||| Neuropsychiatry
Sigma1an + Opioid WLB-73502 |||||||||||||||||| |||||||||||||||||| |||||||||||||||||| |||||||||||||||||| |||||||||||||||||| |||||||||||||||||| Pain
Alpha2Delta1 WLB-74422 WLB86484 |||||||||||||||||| |||||||||||||||||| |||||||||||||||||| Pain
LPAR |||||||||| Pain